Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14232240 | 0.76 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL9772272 | 0.74 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL4874761 | 0.70 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL9401965 | 0.70 | PKM (0.43) | ALDH1A1MAPTKDM4EPKMHPGD | |
| SCHEMBL9772389 | 0.67 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL10642418 | 0.66 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL2558341 | 0.66 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL2551654 | 0.65 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL13568567 | 0.65 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL11847514 | 0.64 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290947-A | Process for the preparation of pyrrole derivates | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0564841-A1 | Process for the preparation of pyrrole derivatives | CASSELLA Aktiengesellschaft (DE) | 1993-10-13 | — | — | EP | disclosed |