Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011883 | 0.72 | PKM (0.50) | PKMKDM4E | |
| SCHEMBL9401952 | 0.70 | ALDH1A1 (0.57) | PKMKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23520606 | 0.65 | RORA (0.55) | PKMKDM4EALDH1A1 | |
| SCHEMBL9093914 | 0.65 | KDM4E (0.33) | KDM4EALDH1A1MAPTALOX15THRB | |
| SCHEMBL6760708 | 0.65 | — | — | |
| SCHEMBL23319549 | 0.64 | HTT (0.62) | KDM4EHTT | |
| SCHEMBL4593870 | 0.64 | MGLL (0.48) | PKMALDH1A1MAPTHPGDHTT | |
| SCHEMBL9772569 | 0.64 | PKM (0.42) | PKMKDM4ETHRB | |
| SCHEMBL563821 | 0.63 | KMT2A (0.47) | PKMALDH1A1HPGD | |
| SCHEMBL15214248 | 0.63 | KDM4E (0.38) | PKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290947-A | Process for the preparation of pyrrole derivates | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0564841-A1 | Process for the preparation of pyrrole derivatives | CASSELLA Aktiengesellschaft (DE) | 1993-10-13 | — | — | EP | disclosed |