Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402286 | 0.82 | POLB (0.43) | KDM4ETLR7 | |
| SCHEMBL9402203 | 0.77 | ALDH1A1 (0.45) | TLR7ALDH1A1 | |
| SCHEMBL9402379 | 0.75 | — | — | |
| SCHEMBL9402365 | 0.73 | TLR7 (0.50) | TLR7 | |
| SCHEMBL9402239 | 0.71 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL29136624 | 0.70 | AGTR1 (0.57) | TLR7 | |
| SCHEMBL9402287 | 0.70 | LMNA (0.51) | ALDH1A1 | |
| SCHEMBL9402219 | 0.70 | — | — | |
| SCHEMBL9402392 | 0.67 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL9087992 | 0.67 | AGTR1 (0.70) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336778-A | Substituted triazoles as angiotensin II antagonists | MERCK & CO., INC. (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0409332-A2 | Substituted triazoles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-23 | — | — | EP | disclosed |