SCHEMBL9404099

SCHEMBL9404099

[c]1nc2ccccc2cc1-c1ncc[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.44
NISCH Q9Y2I1 2/20 0.43
MTOR P42345 1/20 0.43
ADK P55263 1/20 0.43
ALDH1A1 P00352 4/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
ACHE P22303 1/20 0.38
KCNK13 Q9HB14 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CSNK1A1 P48729 1/20 0.35
TYRO3 Q06418 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
IDO1 P14902 1/20 0.35
ADRA2B P18089 5/20 0.33
ADRA2C P18825 5/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2991589 0.76 NPC1 (0.56) MTORALDH1A1HPGDGLAMAPT
SCHEMBL1385432 0.75 ALDH1A1 (0.42) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL4426507 0.74 ALDH1A1 (0.36) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL27489451 0.74 ADRA2A (0.46) ADRA2ANISCHMTORADKALDH1A1
SCHEMBL9763547 0.73 METAP1 (0.51)
SCHEMBL2320187 0.72 KDM4E (0.47) MTORALDH1A1HPGDMAPTKMT2A
SCHEMBL8187067 0.72 PDGFRB (0.35) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL30979447 0.71 ADRA2A (0.46) ADRA2ANISCHMTORADKALDH1A1
SCHEMBL4778401 0.71 CYP1A2 (0.46) ALDH1A1HPGDGLAMAPTACHE
SCHEMBL1288312 0.71 PDGFRB (0.56) ADRA2ANISCHMTORADKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6192240-A None JP disclosed
JP-H06192240-A BENZENEBORINIC ACID DERIVATIVE, PREPARATION THEREOF AND USE THEREOF AS SYNTHETIC INTERMEDIATE SYNTHELABO SA 1994-07-12 JP disclosed