Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | CCR8 | P51685 | 3/20 | 0.43 |
| ▸ | METAP1 | P53582 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719862 | 0.83 | CBFB (0.49) | KDM4ETDP1LMNACCR1CCR5 | |
| SCHEMBL1385432 | 0.82 | ALDH1A1 (0.42) | KDM4ETDP1METAP1CYP1A2POLB | |
| SCHEMBL11160532 | 0.82 | PDGFRB (0.38) | CYP1A2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL724724 | 0.82 | METAP2 (0.44) | CYP1A2SMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL15229223 | 0.81 | ALDH1A1 (0.43) | KDM4EPOLBSMN1; SMN2TP53HTT | |
| SCHEMBL1542711 | 0.80 | DHODH (0.39) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2659111 | 0.78 | NPC1 (0.44) | KDM4ECYP1A2SMN1; SMN2ALOX15HSP90AA1 | |
| SCHEMBL523809 | 0.77 | RAB9A (0.44) | KDM4ETDP1LMNACYP1A2BLM | |
| SCHEMBL5619122 | 0.76 | CYP1A2 (0.35) | KDM4ECYP1A2ALDH1A1HPGDMAPT | |
| SCHEMBL938744 | 0.74 | ALDH1A1 (0.40) | KDM4ETDP1CCR1CCR8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170162800-A1 | Electrically Doped Organic Semiconducting Material and Organic Light Emitting Device Comprising It | NOVALED GMBH (DE) | 2017-06-08 | — | — | US | claimed |
| CN-102918037-A | Carbazole compound having substituent containing electron-accepting nitrogen-containing heteroaryl group, and organic electroluminescent element | JNC CORP | 2013-02-06 | — | — | CN | claimed |
| US-20050288337-A1 | Novel compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-12-29 | — | — | US | claimed |
| EP-1539696-A2 | PROCESS FOR PREPARING QUINOLIN ANTIBIOTIC INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 2005-06-15 | — | — | EP | claimed |
| US-20050004202-A1 | Indazolyl-substituted pyrroline compounds as kinase inhibitors | ZHANG HAN-CHENG (US) | 2005-01-06 | — | — | US | claimed |
| WO-2004014859-A2 | PROCESS FOR PREPARING QUINOLIN ANTIBIOTIC INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 2004-02-19 | — | — | WO | claimed |
| US-6225334-B1 | AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-01 | — | — | US | claimed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | claimed |
| US-5391730-A | An immunsuppressantes, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-02-21 | — | — | US | claimed |
| US-20240201591-A1 | PHOTORESIST UNDERLAYER COMPOSITION | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2024-06-20 | — | — | US | disclosed |
| US-11937504-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2024-03-19 | — | — | US | disclosed |
| CN-117384193-A | Boron-containing organic compound and organic electroluminescent device prepared from same | 江苏三月科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-11411185-B2 | Organic electroluminescent device | UDC IRELAND LIMITED (IE) | 2022-08-09 | — | — | US | disclosed |
| EP-3305871-B1 | USE OF DEUTERATED CARBAZOLE IN ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LTD (IE) | 2020-02-26 | — | — | EP | disclosed |
| US-20040039035-A1 | Modulation of CCR4 function | TULARIK INC. | 2004-02-26 | — | — | US | disclosed |
| US-20020173524-A1 | Modulation of CCR4 function | TULARIK INC. (US) | 2002-11-21 | — | — | US | disclosed |
| WO-2002030358-A2 | MODULATION OF CCR4 FUNCTION | TULARIK INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| US-5766779-A | Electron transporting materials for organic electroluminescent devices | EASTMAN KODAK COMPANY (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1994014797-A1 | QUINOLINE COMPOUNDS AND THE TREATMENT OF LEUCOTRIENE RELATED DISEASES THEREWITH | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |
| US-4851547-A | MALEIC ANHYDRIDE, AMINE TO MALEINAMIC ACID; CATALYST OF STRONG ACID AND/OR ITS AMINE SALT | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288337-A1 | Novel compounds | ITGB4, ITGA4, ITGB5 | KDM4E 810/4885TDP1 3809/4885LMNA 2016/4885 |
| US-20020173524-A1 | Modulation of CCR4 function | CCR4, CCR1, CCR3 | KDM4E 3826/4885TDP1 4118/4885LMNA 4708/4885 |
| US-20170162800-A1 | Electrically Doped Organic Semiconducting Material and Organic Light Emitting Device Comprising It | C1S, C5, HCN2 | KDM4E 3935/4885TDP1 4477/4885LMNA 399/4885 |
| US-20050004202-A1 | Indazolyl-substituted pyrroline compounds as kinase inhibitors | MAP2K2, MAP3K20, MAP2K3 | KDM4E 1504/4885TDP1 687/4885LMNA 3426/4885 |
| US-20040039035-A1 | Modulation of CCR4 function | CCR4, CCR1, CCR3 | KDM4E 3826/4885TDP1 4118/4885LMNA 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.