Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743876 | 0.78 | ADORA2A (0.46) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL859642 | 0.78 | ADORA2A (0.46) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10709057 | 0.76 | ADORA2A (0.48) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL6538264 | 0.76 | ADORA2A (0.57) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL9494041 | 0.76 | ADORA1 (0.46) | ADORA1 | |
| SCHEMBL6829149 | 0.75 | AHCY (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7793907 | 0.73 | ADORA3 (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10710910 | 0.72 | ADORA2A (0.46) | ADORA2AADORA3ADORA1PDE2AADRA1A | |
| SCHEMBL5525776 | 0.72 | PI4KA (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13268818 | 0.72 | PI4KA (0.45) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | claimed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | claimed |