Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7464567 | 0.99 | TAS2R14 (0.40) | TAS2R14KMT2AMEN1PTGESALOX5 | |
| Bromide SCHEMBL8066350 | 0.91 | PTGES (0.45) | TAS2R14KMT2APTGESALOX5ALDH1A1 | |
| Bromide SCHEMBL7459708 | 0.90 | HSP90AA1 (0.50) | TAS2R14KMT2APTGESALDH1A1TAS2R8 | |
| SCHEMBL9407935 | 0.83 | GAA (0.36) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8076562 | 0.79 | MAPT (0.52) | TAS2R14KMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL7469202 | 0.78 | KMT2A (0.48) | KMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL9408007 | 0.78 | KEAP1 (0.41) | PTGESALOX5ALDH1A1 | |
| SCHEMBL7471994 | 0.78 | KEAP1 (0.47) | TAS2R14KMT2APTGESALDH1A1TAS2R8 | |
| SCHEMBL8074295 | 0.77 | MAPT (0.40) | KMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL8076253 | 0.76 | ALDH1A1 (0.42) | PTGESALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257541-A2 | Chemilumuniscent acridine derivatives and their use in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |