SCHEMBL940805

SCHEMBL940805

[CH2]C[Si](C)(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 3/20 0.35
NR1H3 Q13133 3/20 0.35
MGAM O43451 2/20 0.34
TP53 P04637 1/20 0.32
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2971874 0.80 MAPT (0.41) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL386730 0.79 ESR1 (0.39) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9217667 0.78 MAPT (0.47) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL8755988 0.77 ACHE (0.40) MAPTNR1H2NR1H3LMNAACHE
SCHEMBL2974830 0.77 MGAM (0.40) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9226507 0.76 MAPT (0.45) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL16325251 0.75 MAPT (0.38) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL2965525 0.75 MGAM (0.39) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL25284860 0.74 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL6833296 0.74 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
US-20230235202-A1 PLASTICIZER FOR RESINS IDEMITSU KOSAN CO.,LTD. (JP) 2023-07-27 US disclosed
CN-109963886-B Phosphoguanidine group IV metal olefin polymerization catalyst 陶氏环球技术有限责任公司 2023-01-06 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
US-11459409-B2 Catalyst system for multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-04 US disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
EP-3436488-B1 AN OLEFIN POLYMERIZATION CATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-18 EP disclosed
CN-108779205-B Olefin polymerization catalyst 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
US-11214632-B2 Bis-ligated phosphaguanidine group IV metal complexes and olefin polymerization catalysts produced therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2022-01-04 US disclosed
EP-1247814-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-10-09 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
US-20020012872-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-31 US disclosed
EP-1164433-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed
US-5889012-A INSECTICIDE, ACARICIDES, FUNGICIDES HOECHST-SCHERING AGREVO GMBH (DE) 1999-03-30 US disclosed
EP-0714393-B1 THIAZOLES AS ANTIVIRAL PFIZER (US) 1998-09-23 EP disclosed
US-5789408-A Antiviral thiazoles PFIZER INC. (US) 1998-08-04 US disclosed
EP-0714393-A1 THIAZOLES AS ANTIVIRAL PFIZER INC. (US) 1996-06-05 EP disclosed
WO-1995005378-A1 ANTIVIRAL THIAZOLES PFIZER INC. (US) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214632-B2 Bis-ligated phosphaguanidine group IV metal complexes and olefin polymerization catalysts produced therefrom BPGM, POLM, PARG MAPT 2774/4885ESR1 2993/4885ESR2 4167/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 MAPT 4097/4885ESR1 105/4885ESR2 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.