SCHEMBL9408484

SCHEMBL9408484

Cc1cccc(OCC(C)Nc2nc(N)nc(C(C)CF)n2)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.36
MAPT P10636 2/20 0.35
DHFR P00374 1/20 0.35
HTR1B P28222 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
TSHR P16473 2/20 0.34
JAK2 O60674 1/20 0.34
TNF P01375 1/20 0.34
HTT P42858 1/20 0.34
NOD1 Q9Y239 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HTR7 P34969 6/20 0.32
ADRA1D P25100 2/20 0.32
ADRA1A P35348 2/20 0.32
ADRA1B P35368 2/20 0.32
HTR2C P28335 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9291840 0.89 NUDT1 (0.40) NUDT1MAPTDHFRHTR1BNPC1
SCHEMBL10552159 0.82 HSP90AA1 (0.40) NUDT1MAPTDHFRHTR1BNPC1
SCHEMBL7030028 0.78 HTR7 (0.32) HTR7ADRA1DADRA1AADRA1B
SCHEMBL9291907 0.70 ADRB2 (0.41) NPC1RAB9ATSHRNOD1HTR7
SCHEMBL9292056 0.69 MAOA (0.48) NPC1RAB9AHTR7ADRA1DADRA1A
SCHEMBL7700605 0.68 HTR1B (0.56) MAPTHTR1BRAB9AKDM4EGAA
SCHEMBL8984978 0.66 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1B
SCHEMBL9291585 0.66 LMNA (0.40) MAPTKDM4EGAAALDH1A1
SCHEMBL8817579 0.66 HTR1B (0.49) MAPTHTR1BRAB9AHTTKDM4E
SCHEMBL8734802 0.65 HTR7 (0.33) MAPTTSHRHTTHTR7ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6298745-A None JP disclosed
JP-H06298745-A PRODUCTION OF TRIAZINE DERIVATIVE IDEMITSU KOSAN CO LTD 1994-10-25 JP disclosed