Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 7/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408571 | 0.99 | BRAF (0.49) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL8720615 | 0.85 | BRD4 (0.58) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL8718918 | 0.84 | BRD4 (0.57) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL405823 | 0.75 | HTT (0.58) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL536913 | 0.74 | BRAF (0.72) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL29475418 | 0.74 | BRAF (0.72) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL22118772 | 0.72 | BRD4 (0.68) | BRAFCYP1A2SMN1; SMN2HIF1ANPC1 | |
| SCHEMBL160074 | 0.71 | CYP3A4 (0.62) | BRAFCYP1A2SMN1; SMN2HIF1ATSHR | |
| SCHEMBL21914 | 0.71 | HTT (0.62) | CYP1A2SMN1; SMN2HIF1ANPC1RAB9A | |
| SCHEMBL29420373 | 0.71 | CYP3A4 (0.62) | BRAFCYP1A2SMN1; SMN2HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577303-A1 | Stereoselective glycosylation process | ELI LILLY AND COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |