SCHEMBL9408593

SCHEMBL9408593

CN(C)c1ccc(CO)cc1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
SLC6A2 P23975 4/20 0.37
SLC6A4 P31645 4/20 0.37
KIF11 P52732 1/20 0.36
APP P05067 1/20 0.36
HTT P42858 1/20 0.33
EP300 Q09472 1/20 0.33
KAT2B Q92831 1/20 0.33
KAT8 Q9H7Z6 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGS2 P35354 2/20 0.32
SLC6A3 Q01959 2/20 0.32
MAPK1 P28482 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13548280 0.82 TRPA1 (0.39) KIF11MAPK1GAAMAPTTAAR1
SCHEMBL4349492 0.80 LOXL2 (0.41) GAATAAR1
SCHEMBL4349379 0.80 GAA (0.33) HTTPTGS2MAPK1GAATAAR1
SCHEMBL13548266 0.78 CNR1 (0.41) HSD17B10MAPTTAAR1ALDH1A1
Hydrochloric Acid SCHEMBL9408630 0.78 GAA (0.36) HTTPTGS2MAPK1GAATAAR1
SCHEMBL7175390 0.78 RXRA (0.50) RXRARXRBHSD17B10GAAMAPT
SCHEMBL13547901 0.77 ESR1 (0.39)
SCHEMBL26606596 0.74 CYP4F2 (0.39) CYP4F2CYP4A11RXRARXRBHTT
SCHEMBL8467020 0.74 ALDH1A1 (0.49) CYP4F2CYP4A11HTTMAPK1GAA
SCHEMBL24818991 0.73 APP (0.46) APPEP300KAT2BKAT8GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623601-A1 N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1994-11-09 EP disclosed