Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806639 | 0.81 | ALDH1A1 (0.43) | MAPTHTTTDP1ALDH1A1POLB | |
| SCHEMBL8806809 | 0.64 | SCN1A (0.35) | MAPTHTTTSHRUSP2 | |
| SCHEMBL9408149 | 0.63 | MAPT (0.47) | MAPTTP53HTTCTSBTDP1 | |
| SCHEMBL8806234 | 0.63 | HSP90AA1 (0.37) | MAPTHTTTSHRALDH1A1USP2 | |
| SCHEMBL8805917 | 0.63 | DRD2 (0.37) | MAPTTDP1GAAALDH1A1 | |
| SCHEMBL3296949 | 0.59 | SMN1; SMN2 (0.55) | MAPTGAAALDH1A1POLB | |
| SCHEMBL3296952 | 0.59 | SMN1; SMN2 (0.55) | MAPTGAAALDH1A1POLB | |
| SCHEMBL3302195 | 0.59 | SMN1; SMN2 (0.55) | MAPTGAAALDH1A1POLB | |
| SCHEMBL12559695 | 0.59 | POLB (0.42) | HTTTDP1TSHRPOLB | |
| SCHEMBL9483715 | 0.59 | GPR35 (0.42) | MAPTTP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6298757-A | — | — | None | — | — | JP | disclosed |
| JP-H06298757-A | PIPERIDINO-3,4-DIHYDROCARBOSTYRYL DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1994-10-25 | — | — | JP | disclosed |