Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409179 | 0.90 | GAA (0.46) | GAAKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9409100 | 0.83 | MAPT (0.59) | GAAKDM4EALDH1A1HSD17B10SIRT2 | |
| SCHEMBL9409083 | 0.82 | MAPT (0.61) | GAAKDM4EALDH1A1HSD17B10SIRT2 | |
| SCHEMBL9409337 | 0.81 | CSF1R (0.49) | KDM4EALDH1A1HSD17B10SIRT2SMN1; SMN2 | |
| SCHEMBL9409108 | 0.81 | TSHR (0.51) | GAAKDM4EALDH1A1HSD17B10SIRT2 | |
| SCHEMBL9409163 | 0.80 | MAPT (0.50) | KDM4EALDH1A1HSD17B10SIRT2SMN1; SMN2 | |
| SCHEMBL9409146 | 0.80 | JAK2 (0.54) | GAAKDM4EALDH1A1HSD17B10SIRT2 | |
| SCHEMBL9409047 | 0.80 | MAPT (0.55) | KDM4ESIRT2MAPTPOLBMEN1 | |
| SCHEMBL9409103 | 0.78 | ALDH1A1 (0.50) | GAAKDM4EALDH1A1HSD17B10SIRT2 | |
| SCHEMBL9409202 | 0.77 | MAPT (0.64) | GAAALDH1A1HSD17B10SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |