Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409102 | 0.90 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL1994444 | 0.69 | MAPT (0.43) | CFTRKDM4ESOS1MAPTALDH1A1 | |
| SCHEMBL522786 | 0.67 | CA12 (0.47) | CFTRKDM4ESOS1MAPTALDH1A1 | |
| SCHEMBL20511627 | 0.67 | CA12 (0.47) | CFTRKDM4ESOS1MAPTALDH1A1 | |
| SCHEMBL1957013 | 0.66 | SLC6A4 (0.46) | CFTRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL1957011 | 0.66 | SLC6A4 (0.46) | CFTRKDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL829400 | 0.66 | DGAT1 (0.45) | CASP1CA12CA1CA2CA7 | |
| SCHEMBL28085635 | 0.66 | DGAT1 (0.45) | CASP1CA12CA1CA2CA7 | |
| SCHEMBL10364420 | 0.65 | KDM4E (0.50) | CFTRKDM4ESOS1MAPTALDH1A1 | |
| SCHEMBL19680526 | 0.65 | ALDH1A1 (0.49) | KDM4EMAPTALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |