Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 5/20 | 0.45 |
| ▸ | JAK3 | P52333 | 5/20 | 0.45 |
| ▸ | JAK2 | O60674 | 4/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409103 | 0.91 | ALDH1A1 (0.50) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL1548694 | 0.80 | ALDH1A1 (0.54) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL9409050 | 0.79 | CSF1R (0.49) | MAPTALDH1A1GAAKDM4ERAB9A | |
| SCHEMBL30664049 | 0.79 | JAK1 (0.50) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL29127165 | 0.79 | JAK1 (0.50) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL9409045 | 0.77 | KDM4E (0.53) | MAPTALDH1A1GAAKDM4ESIRT2 | |
| SCHEMBL9409092 | 0.77 | CDC25B (0.63) | MAPTALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL9409089 | 0.76 | FABP4 (0.61) | MAPTKDM4EPTGS2SIRT2 | |
| SCHEMBL9409079 | 0.76 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL27516871 | 0.76 | CLCN2 (0.76) | MAPTALDH1A1GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |