Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834288 | 0.92 | MAPT (0.51) | SIRT2MAPTALOX15ALDH1A1NPC1 | |
| SCHEMBL2391240 | 0.89 | MEN1 (0.50) | SIRT2CSF1RMAPTALDH1A1MEN1 | |
| SCHEMBL9409094 | 0.87 | SIRT2 (0.54) | SIRT2MAPTALOX15ALDH1A1NPC1 | |
| SCHEMBL9409132 | 0.85 | AKR1C3 (0.55) | SIRT2CSF1RMAPTALOX15NPC1 | |
| SCHEMBL9409202 | 0.85 | MAPT (0.64) | SIRT2MAPTALOX15ALDH1A1 | |
| SCHEMBL9409093 | 0.85 | LMNA (0.52) | SIRT2CSF1RMAPTALOX15NPC1 | |
| SCHEMBL9409210 | 0.84 | SIRT2 (0.58) | SIRT2MAPTALOX15ALDH1A1NPC1 | |
| SCHEMBL9409188 | 0.84 | SIRT2 (0.51) | SIRT2MAPTALOX15ALDH1A1NPC1 | |
| SCHEMBL9409084 | 0.83 | SIRT2 (0.73) | SIRT2MAPTALOX15ALDH1A1MEN1 | |
| SCHEMBL9409105 | 0.82 | SIRT2 (0.49) | SIRT2CSF1RMAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |