Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 6/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409184 | 0.91 | SYK (0.57) | AKR1C3AKR1C2SYKCSF1RSIRT2 | |
| SCHEMBL9409062 | 0.86 | SIRT2 (0.47) | SIRT2MAPTALOX15SIRT1MAPK1 | |
| SCHEMBL9409034 | 0.86 | ALDH1A1 (0.56) | AKR1C3AKR1C2SIRT2MAPTALOX15 | |
| SCHEMBL9409202 | 0.85 | MAPT (0.64) | AKR1C3AKR1C2SIRT2MAPTALOX15 | |
| SCHEMBL9409093 | 0.85 | LMNA (0.52) | CSF1RSIRT2MAPTALOX15SIRT1 | |
| SCHEMBL9409049 | 0.85 | AKR1C3 (0.58) | AKR1C3AKR1C2SYKSIRT2MAPT | |
| SCHEMBL9409094 | 0.84 | SIRT2 (0.54) | AKR1C3AKR1C2SIRT2MAPTALOX15 | |
| SCHEMBL9409168 | 0.84 | AKR1C3 (0.56) | AKR1C3AKR1C2SIRT2MAPTALOX15 | |
| SCHEMBL9409026 | 0.84 | SIRT2 (0.55) | SYKSIRT2MAPTALOX15SIRT1 | |
| SCHEMBL9409059 | 0.83 | ALDH1A1 (0.58) | AKR1C3AKR1C2SIRT2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |