Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409500 | 0.94 | HDAC4 (0.48) | HDAC4HDAC6LCKJAK3KDM4E | |
| SCHEMBL9409396 | 0.86 | HTR2A (0.49) | HTR2ADRD3DRD2KMT2ALMNA | |
| SCHEMBL4181896 | 0.83 | HDAC4 (0.57) | HDAC4HDAC6LCKJAK3KDM4E | |
| SCHEMBL9409398 | 0.82 | HTR2A (0.52) | HDAC4HDAC6HTR2ADRD3DRD2 | |
| SCHEMBL9409599 | 0.81 | HTR2A (0.44) | KDM4EHTR2ADRD3DRD2LMNA | |
| SCHEMBL9409417 | 0.80 | HRH3 (0.52) | HTR2ADRD3DRD2LMNA | |
| SCHEMBL9409528 | 0.79 | HDAC4 (0.41) | HDAC4HDAC6USP30KDM4EPKM | |
| SCHEMBL9409411 | 0.79 | NAMPT (0.47) | PDE4BKDM4EPKML3MBTL1LMNA | |
| SCHEMBL9409552 | 0.79 | KMT2A (0.51) | HDAC4HDAC6LCKJAK3KDM4E | |
| SCHEMBL9409412 | 0.78 | PDE4B (0.59) | PDE4BUSP30KDM4EPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |