Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409500 | 0.81 | HDAC4 (0.48) | HDAC4KDM4EPKML3MBTL1HDAC6 | |
| SCHEMBL9409541 | 0.79 | PDE4B (0.46) | HDAC4KDM4EPKML3MBTL1HDAC6 | |
| Hydrochloric Acid SCHEMBL9409522 | 0.78 | OPRM1 (0.39) | HDAC4HDAC6KMT2ADRD2MEN1 | |
| SCHEMBL9409426 | 0.77 | PKM (0.48) | PKMHDAC6KMT2AMEN1HDAC1 | |
| SCHEMBL9409509 | 0.74 | RORC (0.44) | KMT2AUSP30MEN1HDAC1GPR119 | |
| SCHEMBL9409396 | 0.73 | HTR2A (0.49) | KMT2ADRD2HTR2ADRD3MEN1 | |
| SCHEMBL30127217 | 0.71 | NR1H2 (0.47) | L3MBTL1KMT2AUSP30MEN1HDAC1 | |
| SCHEMBL27099790 | 0.71 | TSHR (0.52) | USP30GPR119TSHR | |
| Hydrochloric Acid SCHEMBL9409530 | 0.70 | OPRM1 (0.38) | HDAC4HDAC6KMT2ADRD2HTR2A | |
| SCHEMBL9288197 | 0.70 | CA1 (0.42) | HDAC6DRD2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |