SCHEMBL941002

SCHEMBL941002

O=C(O)c1cccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 2/20 0.62
TYR P14679 2/20 0.58
SLC5A1 P13866 2/20 0.57
SLC5A2 P31639 1/20 0.57
TYMP P19971 1/20 0.56
HIF1A Q16665 1/20 0.55
USP2 O75604 4/20 0.53
HKDC1 Q2TB90 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
TNNI3 P19429 2/20 0.53
TNNT2 P45379 2/20 0.53
TNNC1 P63316 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
GLA P06280 1/20 0.53
CYP3A4 P08684 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4281885 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL8654543 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL8654092 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL8659653 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL28176940 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL14164007 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL244406 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL29382560 0.88 SLC5A2 (0.64) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL942732 0.86 SLC28A3 (0.62) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL941049 0.84 SLC28A3 (0.60) SLC28A3TYRSLC5A1SLC5A2TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8268868-A None JP disclosed
JP-8268871-A None JP disclosed
JP-8268870-A None JP disclosed
JP-8268869-A None JP disclosed
JP-8268872-A None JP disclosed
EP-1932514-B1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR EZAKI GLICO CO (JP) 2018-11-14 EP disclosed
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 US disclosed
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE DSM IP ASSETS B.V. (NL) 2011-01-20 US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 US disclosed
EP-1932514-A1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR Ezaki Glico Co., Ltd. (JP) 2008-06-18 EP disclosed
EP-1859835-A2 Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside PENTAPHARM Ltd. (CH) 2007-11-28 EP disclosed
US-20030198610-A1 Topical agent for dermatological use DSM IP ASSETS B.V. (NL) 2003-10-23 US disclosed
EP-1289489-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM Ltd. (CH) 2003-03-12 EP disclosed
WO-2001091715-A2 TOPICAL AGENT FOR DERMATOLOGICAL USE CONTAINING 4-HYDROXYPHENYL-ALPHA-D-GLUCOPYRANOSIDE PENTAPHARM LTD. (CH) 2001-12-06 WO disclosed
EP-0649648-B1 Skin whitening agents containing glycosides SHISEIDO CO LTD (JP) 2001-09-19 EP disclosed
JP-H08268871-A COSMETIC SHISEIDO CO LTD 1996-10-15 JP disclosed
JP-H08268868-A DERMAL PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD 1996-10-15 JP disclosed
JP-H08268870-A DERMAL PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD 1996-10-15 JP disclosed
JP-H08268872-A DERMAL PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD 1996-10-15 JP disclosed
JP-H08268869-A DERMAL PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD 1996-10-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE GALE, ALPP, UGGT1 SLC28A3 2245/4885TYR 9/4885SLC5A1 1371/4885
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 SLC28A3 1164/4885TYR 149/4885SLC5A1 723/4885
US-20030198610-A1 Topical agent for dermatological use GALE, UGGT1, UGDH SLC28A3 2040/4885TYR 6/4885SLC5A1 1242/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 SLC28A3 977/4885TYR 113/4885SLC5A1 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.