SCHEMBL942732

SCHEMBL942732

COC(=O)c1cccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC28A3 Q9HAS3 3/20 0.62
TYR P14679 1/20 0.60
SLC5A1 P13866 3/20 0.54
SLC5A2 P31639 2/20 0.54
APP P05067 1/20 0.52
HIF1A Q16665 1/20 0.52
SNCA P37840 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941049 0.88 SLC28A3 (0.60) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL941797 0.87 SLC28A3 (0.58) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL941002 0.86 SLC28A3 (0.62) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL940123 0.86 SLC28A3 (0.57) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL4636191 0.85 SLC28A3 (0.61) SLC28A3SLC5A1SLC5A2APPHIF1A
SCHEMBL940443 0.84 SLC28A3 (0.78) SLC28A3TYRSLC5A1APPHIF1A
SCHEMBL1315789 0.83 TYR (0.77) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL7780293 0.83 SLC28A3 (0.53) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL7773544 0.83 SLC28A3 (0.53) SLC28A3TYRSLC5A1SLC5A2HIF1A
SCHEMBL4635920 0.81 SLC28A3 (0.58) SLC28A3TYRAPPSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932514-B1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR EZAKI GLICO CO (JP) 2018-11-14 EP disclosed
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 US disclosed
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE DSM IP ASSETS B.V. (NL) 2011-01-20 US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 US disclosed
EP-1859835-A2 Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside PENTAPHARM Ltd. (CH) 2007-11-28 EP disclosed
US-20030198610-A1 Topical agent for dermatological use DSM IP ASSETS B.V. (NL) 2003-10-23 US disclosed
EP-0649648-B1 Skin whitening agents containing glycosides SHISEIDO CO LTD (JP) 2001-09-19 EP disclosed
US-5700784-A GLYCOSIDES OF HYDROXYSALICYLIC ACID AND/OR GLYCOSIDES OF ESTERS OF HYDROXYSALICYLIC ACID; EXCELLENT WHITENING EFFECT AND SKIN CARE EFFECT SHISEIDO CO., LTD. (JP) 1997-12-23 US disclosed
EP-0649648-A2 Skin whitening agents containing glycosides SHISEIDO COMPANY LIMITED (JP) 1995-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014141-A1 TOPICAL AGENT FOR DERMATOLOGICAL USE GALE, ALPP, UGGT1 SLC28A3 2245/4885TYR 9/4885SLC5A1 1371/4885
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 SLC28A3 1164/4885TYR 149/4885SLC5A1 723/4885
US-20030198610-A1 Topical agent for dermatological use GALE, UGGT1, UGDH SLC28A3 2040/4885TYR 6/4885SLC5A1 1242/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 SLC28A3 977/4885TYR 113/4885SLC5A1 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.