Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410555 | 0.83 | APP (0.44) | KDM4ETRPM8ALDH1A1HPGDPOLB | |
| SCHEMBL9410548 | 0.78 | KDM4E (0.67) | KDM4EALDH1A1HPGDUSP2MEN1 | |
| SCHEMBL9524768 | 0.72 | TRPM8 (0.40) | KDM4ETRPM8ALDH1A1POLBMEN1 | |
| SCHEMBL9410545 | 0.71 | KMT2A (0.46) | KDM4EALDH1A1HPGDUSP2MEN1 | |
| SCHEMBL9410581 | 0.70 | NPC1 (0.51) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL10643357 | 0.68 | POLB (0.39) | KDM4ETRPM8POLBMEN1KMT2A | |
| SCHEMBL9410592 | 0.67 | RAB9A (0.56) | ALDH1A1POLBKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6316045 | 0.64 | TSHR (0.58) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL18765244 | 0.64 | GAA (0.57) | ALDH1A1KMT2ANPSR1HSD17B10GAA | |
| SCHEMBL761922 | 0.64 | ALOX15 (0.45) | KDM4ETRPM8ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624575-A1 | Substituted indoles and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |