SCHEMBL941091

SCHEMBL941091

S=C=NCC1CCCC(CN=C=S)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
NAAA Q02083 1/20 0.33
APLNR P35414 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isothiocyanate SCHEMBL17289573 0.93 KEAP1 (0.32) KEAP1NFE2L2NAAA
SCHEMBL11053867 0.90
SCHEMBL6538414 0.84
(Isothiocyanatomethyl)Cyclohexane SCHEMBL1448756 0.82 KEAP1 (0.42) KEAP1NFE2L2NAAAAPLNR
SCHEMBL2143495 0.78 APLNR (0.36) KEAP1NFE2L2NAAAAPLNR
SCHEMBL569528 0.78
SCHEMBL26614265 0.78 APLNR (0.36) KEAP1NFE2L2NAAAAPLNR
SCHEMBL20462167 0.78 ALDH1A1 (0.31)
SCHEMBL43488 0.78 ALDH1A1 (0.31)
SCHEMBL1069199 0.78 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250032470-A1 Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells WAYNE STATE UNIVERSITY (US) 2025-01-30 US claimed
EP-3743453-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS Novol, Inc. (US) 2020-12-02 EP claimed
US-20200354507-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. 2020-11-12 US claimed
US-10696778-B1 Methods of making polymers using isosorbide NOVOL, INC. (US) 2020-06-30 US claimed
WO-2019147848-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. (US) 2019-08-01 WO claimed
US-20250032470-A1 Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells WAYNE STATE UNIVERSITY (US) 2025-01-30 US disclosed
US-12133846-B2 Electrophilic androgen receptor (AR) antagonists for AR downregulation and ferroptosis induction in cancer cells WAYNE STATE UNIVERSITY (US) 2024-11-05 US disclosed
US-11780950-B1 Methods of making polymers using isosorbide Bhatia, Monica (US) 2023-10-10 US disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
EP-3572202-B1 MOLDED ARTICLE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL CO (JP) 2021-08-11 EP disclosed
US-10941254-B2 Molded article and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-09 US disclosed
EP-3743453-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS Novol, Inc. (US) 2020-12-02 EP disclosed
US-20110021916-A1 ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE MATERIAL, METHOD FOR MANUFACTURING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE, AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-01-27 US disclosed
US-20110004102-A1 ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE SAME, METHOD FOR PRODUCING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-01-06 US disclosed
EP-1319966-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-05-26 EP disclosed
US-20100029890-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND PROCESS FOR PRODUCING THE RESIN MITSUI CHEMICALS, INC. (JP) 2010-02-04 US disclosed
EP-2065414-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE RESIN Mitsui Chemicals, Inc. (JP) 2009-06-03 EP disclosed
US-7009031-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2006-03-07 US disclosed
US-20040024165-A1 Composition for optical material MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-02-05 US disclosed
EP-1319966-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029890-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND PROCESS FOR PRODUCING THE RESIN OXGR1, HRH3, HRH4 KEAP1 1787/4885NFE2L2 2663/4885NAAA 2822/4885
US-12133846-B2 Electrophilic androgen receptor (AR) antagonists for AR downregulation and ferroptosis induction in cancer cells AR, GSR, GPX1 KEAP1 11/4885NFE2L2 17/4885NAAA 842/4885
US-11780950-B1 Methods of making polymers using isosorbide PUF60, MACF1, PPIE KEAP1 1133/4885NFE2L2 3136/4885NAAA 1464/4885
US-20250032470-A1 Electrophilic Androgen Receptor (AR) Antagonists for AR Downregulation and Ferroptosis Induction in Cancer Cells AR, GSR, GPX1 KEAP1 11/4885NFE2L2 17/4885NAAA 842/4885
US-10696778-B1 Methods of making polymers using isosorbide PUF60, MACF1, PPIE KEAP1 938/4885NFE2L2 3237/4885NAAA 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.