Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941091 | 0.93 | KEAP1 (0.34) | KEAP1NFE2L2NAAA | |
| SCHEMBL11053867 | 0.84 | — | — | |
| SCHEMBL6538414 | 0.79 | — | — | |
| SCHEMBL6510103 | 0.77 | — | — | |
| (Isothiocyanatomethyl)Cyclohexane SCHEMBL1448756 | 0.77 | KEAP1 (0.42) | KEAP1NFE2L2NAAA | |
| Methane SCHEMBL4900676 | 0.75 | — | — | |
| SCHEMBL26614265 | 0.73 | APLNR (0.36) | KEAP1NFE2L2NAAA | |
| SCHEMBL569528 | 0.73 | — | — | |
| SCHEMBL2143495 | 0.73 | APLNR (0.36) | KEAP1NFE2L2NAAA | |
| SCHEMBL20462167 | 0.73 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344613-A1 | POLYTHIOUREA COMPOSITIONS AND METHODS OF USE | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344613-A1 | POLYTHIOUREA COMPOSITIONS AND METHODS OF USE | PNMT, SRM, PUF60 | KEAP1 865/4885NFE2L2 2596/4885NAAA 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.