Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867391 | 0.81 | DHODH (0.51) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8867889 | 0.76 | PSMB5 (0.45) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1398196 | 0.74 | CYP1A2 (0.41) | KDM4EHTTKMT2ASMN1; SMN2ESR1 | |
| SCHEMBL8867753 | 0.74 | TLR7 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8967010 | 0.73 | MET (0.44) | HTTPDGFRBPDGFRAPSMB5CAMKK2 | |
| SCHEMBL27190487 | 0.73 | KDM4E (0.59) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9411413 | 0.73 | PDE4B (0.43) | HTTKMT2ADHODH | |
| SCHEMBL9414452 | 0.71 | EGLN1 (0.40) | HTTKMT2ADHODHEGLN1 | |
| SCHEMBL247376 | 0.70 | PTGDR2 (0.52) | KMT2AKMOPTGDR2ESR1ESR2 | |
| SCHEMBL14775410 | 0.69 | CXCR5 (0.43) | KDM4EKMT2AKMOPTGDR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627427-A1 | 3-Quinolyl substituted dihydropyridines, process for their preparation and their use in drugs | BAYER AG (DE) | 1994-12-07 | — | — | EP | disclosed |