Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9411612 | 1.00 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL9411480 | 0.92 | ACHE (0.77) | ACHEBCHE | |
| Maleic Acid SCHEMBL6990290 | 0.89 | ACHE (0.85) | ACHEBCHE | |
| Maleic Acid SCHEMBL6989248 | 0.89 | ACHE (0.85) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6989253 | 0.89 | ACHE (0.85) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6990295 | 0.89 | ACHE (0.85) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6986323 | 0.89 | ACHE (0.84) | ACHEBCHE | |
| Maleic Acid SCHEMBL6986318 | 0.89 | ACHE (0.84) | ACHEBCHE | |
| Maleic Acid SCHEMBL27339109 | 0.89 | ACHE (0.84) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6986325 | 0.89 | ACHE (0.84) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6041125-A | — | — | None | — | — | JP | disclosed |
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| JP-H0641125-A | BENZOISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUT IND LTD | 1994-02-15 | — | — | JP | disclosed |
| JP-H00641125-A | — | — | 0001-01-01 | — | — | JP | disclosed |