Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412435 | 0.93 | ITGB3 (0.46) | HTR4MAPTITGB3ITGA2B | |
| SCHEMBL9412685 | 0.90 | ITGB3 (0.38) | MAPTSMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL9412438 | 0.90 | ITGB3 (0.38) | MAPTITGB3ITGA2B | |
| SCHEMBL9412599 | 0.90 | HTR4 (0.38) | HTR4MAPTITGB3ITGA2B | |
| SCHEMBL9412627 | 0.88 | ITGB3 (0.37) | ITGB3ITGA2BPTGES | |
| SCHEMBL9412623 | 0.84 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL9412536 | 0.84 | ITGB3 (0.46) | MAPTSMN1; SMN2ROCK2ITGB3ITGA2B | |
| Bromide SCHEMBL9412481 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL9412665 | 0.79 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL9412511 | 0.79 | MAPT (0.45) | MAPTSMN1; SMN2NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |