Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9412670 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPDE10A | |
| SCHEMBL9412685 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BPOLB | |
| SCHEMBL9412599 | 0.88 | HTR4 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9412438 | 0.88 | ITGB3 (0.38) | ITGB3ITGA2BPOLB | |
| SCHEMBL9412475 | 0.88 | HTR4 (0.42) | ITGB3ITGA2BPTGES | |
| SCHEMBL9412536 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BPOLB | |
| SCHEMBL9412623 | 0.83 | MAPT (0.46) | ITGB3ITGA2BPOLB | |
| SCHEMBL9412435 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL9412452 | 0.79 | MAPT (0.44) | ITGB3ITGA2BPOLB | |
| Bromide SCHEMBL9412481 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |