Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 10/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416573 | 0.93 | HSD17B1 (0.50) | HSD17B1HSD17B2ENPP2OPRM1OPRD1 | |
| SCHEMBL19049387 | 0.84 | HSD17B2 (0.61) | HSD17B1HSD17B2 | |
| SCHEMBL7776491 | 0.80 | CYP1A2 (0.46) | — | |
| SCHEMBL2117209 | 0.78 | LMNA (0.62) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9416588 | 0.77 | HSD17B2 (0.57) | HSD17B2HDAC6 | |
| SCHEMBL13180006 | 0.77 | HSD17B2 (0.47) | HSD17B1HSD17B2DRD2DRD1DRD4 | |
| SCHEMBL31126663 | 0.76 | ALDH1A1 (0.54) | HSD17B1HSD17B2ENPP2OPRM1OPRD1 | |
| SCHEMBL9416589 | 0.76 | ENPP2 (0.54) | HSD17B1HSD17B2ENPP2OPRM1OPRD1 | |
| SCHEMBL9416644 | 0.76 | ALDH1A1 (0.50) | CYP3A4CHRM2CHRM1CHRM3 | |
| SCHEMBL234552 | 0.76 | ALDH1A1 (0.54) | HSD17B1HSD17B2ENPP2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |