Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 11/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536329 | 1.00 | PKM (0.47) | PKMSIGMAR1CXCR4CXCL12KDM4E | |
| Acetic Acid SCHEMBL9714221 | 0.89 | CXCR4 (0.45) | PKMSIGMAR1CXCR4KDM4EKMT2A | |
| SCHEMBL9417365 | 0.89 | SIGMAR1 (0.42) | PKMSIGMAR1CXCR4CXCL12KDM4E | |
| SCHEMBL9417354 | 0.89 | SIGMAR1 (0.42) | PKMSIGMAR1CXCR4CXCL12KDM4E | |
| SCHEMBL172975 | 0.87 | PKM (0.55) | PKMSIGMAR1CXCR4CXCL12KDM4E | |
| SCHEMBL14107151 | 0.85 | PKM (0.52) | PKMSIGMAR1CXCR4CXCL12KDM4E | |
| SCHEMBL13744511 | 0.82 | ALDH1A1 (0.49) | PKMSIGMAR1CXCR4KDM4EKMT2A | |
| SCHEMBL8851659 | 0.80 | KMT2A (0.38) | PKMSIGMAR1CXCR4KMT2ASMN1; SMN2 | |
| SCHEMBL8851721 | 0.80 | GNAI3 (0.58) | SIGMAR1CXCR4KMT2ASMN1; SMN2 | |
| SCHEMBL9452575 | 0.80 | KMT2A (0.50) | CXCR4CXCL12KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| EP-0243449-A1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002367-A2 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | claimed |
| US-5373095-A | Steroid compounds | THE UPJOHN COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5334712-A | Estrane or androstane pyridinyl alkyl or alkylphenyl amine steroids for antidiabetes and obesity | THE UPJOHN COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| US-5274089-A | A estra-1,3,5(10)-triene derivative | THE UPJOHN COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5187299-A | Phospholipase inhibitors; treating diabetes, obesity | THE UPJOHN COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| US-5145874-A | Phospholipase inhibitor, hypoglycemic agent, antidiabetic, obesity | THE UPJOHN COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-4917826-A | TREATING DIABETES AND OBESITY | THE UPJOHN COMPANY (US) | 1990-04-17 | — | — | US | disclosed |