Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 11/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951516 | 0.94 | KMT2A (0.44) | KMT2ACXCR4CXCL12KDM4ELMNA | |
| SCHEMBL15884117 | 0.90 | GNAI3 (0.40) | KMT2AKDM4ELMNAGNAI3GNAO1 | |
| SCHEMBL8851486 | 0.81 | LMNA (0.35) | KMT2ALMNAGNAI3GNAO1GNAI1 | |
| SCHEMBL8851547 | 0.81 | GNAI3 (0.59) | KMT2ACXCR4LMNAGNAI3GNAO1 | |
| SCHEMBL9417348 | 0.80 | PKM (0.47) | KMT2ACXCR4CXCL12KDM4E | |
| SCHEMBL3536329 | 0.80 | PKM (0.47) | KMT2ACXCR4CXCL12KDM4E | |
| SCHEMBL22210657 | 0.79 | CXCR4 (0.41) | CXCR4CXCL12KDM4E | |
| SCHEMBL12083018 | 0.78 | LMNA (0.40) | KMT2ALMNA | |
| SCHEMBL3687839 | 0.77 | GNAI3 (0.52) | KMT2ACXCR4CXCL12KDM4EGNAI3 | |
| SCHEMBL7775131 | 0.77 | GNAI3 (0.52) | KMT2ACXCR4CXCL12KDM4EGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196542-A | Phospholipase A2 inhibitors | THE UPJOHN COMPANY (US) | 1993-03-23 | — | — | US | disclosed |