Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163750 | 0.82 | KMT2A (0.45) | KMT2AALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL9172738 | 0.79 | PLA2G2A (0.53) | — | |
| SCHEMBL9170924 | 0.77 | CETP (0.45) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9165252 | 0.77 | TSHR (0.51) | ALDH1A1NPC1RAB9A | |
| SCHEMBL9163745 | 0.76 | NAAA (0.54) | NAAASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL24526930 | 0.75 | SMN1; SMN2 (0.51) | NAAASIGMAR1TMEM97SMN1; SMN2KMT2A | |
| SCHEMBL9168493 | 0.74 | PLA2G2A (0.44) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL131829 | 0.74 | SMN1; SMN2 (0.87) | NAAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6535127 | 0.74 | SMN1; SMN2 (0.87) | NAAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9165612 | 0.74 | NAAA (0.50) | NAAASMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |