Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 11/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539514 | 0.98 | LMNA (0.70) | LMNAHTTDNM1HSP90AA1RAD52 | |
| SCHEMBL12412127 | 0.98 | LMNA (0.70) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9418658 | 0.96 | LMNA (0.62) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9418670 | 0.96 | LMNA (0.62) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9418686 | 0.89 | LMNA (0.53) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL12096450 | 0.87 | LMNA (0.69) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL2548504 | 0.85 | LMNA (0.68) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL15422634 | 0.84 | LMNA (0.56) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28963644 | 0.84 | LMNA (0.56) | LMNAHTTDNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL23754402 | 0.83 | LMNA (0.96) | LMNAHTTDNM1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281414-A | Crosslinked organosilicon quarternary ammonium salt and ion exchange resin | STOCKEL RICHARD F (US) | 1994-01-25 | — | — | US | claimed |
| US-4921691-A | Spray on wound dressing compositions | STOCKEL RICHARD F (US) | 1990-05-01 | — | — | US | claimed |
| CN-122095116-A | Coated steel sheet and method for producing same | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2026105851-A1 | SURFACE-TREATED STEEL MATERIAL AND SURFACE-TREATED MEMBER | 日本製鉄株式会社 | 2026-05-21 | — | — | WO | disclosed |
| CN-224240602-U | Organosilicon article | 深圳市西陆新材料科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12534631-B2 | Pre-coated metal sheet | NIPPON STEEL CORPORATION (JP) | 2026-01-27 | — | — | US | disclosed |
| EP-4681915-A1 | SURFACE-TREATED STEEL SHEET | NIPPON STEEL CORPORATION (JP) | 2026-01-21 | — | — | EP | disclosed |
| US-12497519-B2 | Pre-coated plated steel sheet and molded product | NIPPON STEEL CORPORATION (JP) | 2025-12-16 | — | — | US | disclosed |
| US-12492478-B2 | Coated and plated steel sheet or coated and plated steel strip | NIPPON STEEL CORPORATION (JP) | 2025-12-09 | — | — | US | disclosed |
| EP-4275885-B1 | PRE-COATED PLATED STEEL SHEET AND MOLDED PRODUCT | NIPPON STEEL CORP (JP) | 2025-11-19 | — | — | EP | disclosed |
| EP-4644115-A1 | SURFACE-TREATED STEEL SHEET | NIPPON STEEL CORPORATION (JP) | 2025-11-05 | — | — | EP | disclosed |
| EP-3950318-A1 | METAL-CARBON FIBER REINFORCED RESIN MATERIAL COMPOSITE AND METHOD FOR MANUFACTURING METAL-CARBON FIBER REINFORCED RESIN MATERIAL COMPOSITE | NIPPON STEEL CORPORATION (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20210154978-A1 | METAL-CARBON FIBER REINFORCED PLASTIC COMPOSITE AND METHOD FOR MANUFACTURING METAL-CARBON FIBER REINFORCED PLASTIC COMPOSITE | NIPPON STEEL CORPORATION (JP) | 2021-05-27 | — | — | US | disclosed |
| EP-3778209-A1 | METAL-CARBON FIBER REINFORCED RESIN MATERIAL COMPOSITE AND PRODUCTION METHOD FOR METAL-CARBON FIBER REINFORCED RESIN MATERIAL COMPOSITE | NIPPON STEEL CORPORATION (JP) | 2021-02-17 | — | — | EP | disclosed |
| CN-111655475-A | Metal-carbon fiber reinforced resin material composite and method for producing metal-carbon fiber reinforced resin material composite | 日本制铁株式会社 | 2020-09-11 | — | — | CN | disclosed |
| US-9428823-B2 | Surface-treated steel sheet and method of manufacturing the same | NIPPON STEEL & SUMITOMO METAL CORPORATION (JP) | 2016-08-30 | — | — | US | disclosed |
| US-20140023879-A1 | SURFACE-TREATED STEEL SHEET AND METHOD OF MANUFACTURING THE SAME | NIPPON STEEL CORPORATION (JP) | 2014-01-23 | — | — | US | disclosed |
| US-5281414-A | Crosslinked organosilicon quarternary ammonium salt and ion exchange resin | STOCKEL RICHARD F (US) | 1994-01-25 | — | — | US | disclosed |
| US-4921691-A | Spray on wound dressing compositions | STOCKEL RICHARD F (US) | 1990-05-01 | — | — | US | disclosed |
| US-4615882-A | NON ADSORBABLE ORGANOSILICON QUATERNARY AMMONIUM SALT BONDED TO WATER-SOLUBLE POLYMER | STOCKEL RICHARD F | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534631-B2 | Pre-coated metal sheet | SLC30A7, SOD1, ITGB7 | LMNA 1311/4885HTT 3958/4885DNM1 1803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.