Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9418656 | 0.89 | LMNA (0.68) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| SCHEMBL12412127 | 0.87 | LMNA (0.70) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| SCHEMBL18539514 | 0.87 | LMNA (0.70) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL9418670 | 0.85 | LMNA (0.62) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL9418658 | 0.85 | LMNA (0.62) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL1133699 | 0.83 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10580785 | 0.83 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL234192 | 0.83 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL1133981 | 0.83 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10389453 | 0.83 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281414-A | Crosslinked organosilicon quarternary ammonium salt and ion exchange resin | STOCKEL RICHARD F (US) | 1994-01-25 | — | — | US | disclosed |
| US-4921691-A | Spray on wound dressing compositions | STOCKEL RICHARD F (US) | 1990-05-01 | — | — | US | disclosed |
| US-4615882-A | NON ADSORBABLE ORGANOSILICON QUATERNARY AMMONIUM SALT BONDED TO WATER-SOLUBLE POLYMER | STOCKEL RICHARD F | 1986-10-07 | — | — | US | disclosed |