SCHEMBL9419503

SCHEMBL9419503

C=CCc1ccc(C2(C)CO2)cc1.C=CCc1ccccc1C1(C)CO1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.34
MAPT P10636 1/20 0.34
ADRA2A P08913 3/20 0.30
ADRA2B P18089 3/20 0.30
ADRA2C P18825 3/20 0.30
HTR1A P08908 2/20 0.30
KCNH2 Q12809 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30
CYP26A1 O43174 1/20 0.30
CYP26B1 Q9NR63 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2829867 0.89 GABRA1 (0.37) ALDH1A1MAPTADRA2AADRA2BADRA2C
SCHEMBL2828921 0.85 ALDH1A1 (0.44) CYP3A4ALDH1A1TP53ALOX15TSHR
SCHEMBL8470328 0.70 POLB (0.37) ALDH1A1
SCHEMBL7859067 0.67 ADRB2 (0.34) ALDH1A1ADRA2AADRA2BADRA2CHTR1A
SCHEMBL1499439 0.66 CHRNB2 (0.35) CYP3A4ALDH1A1CYP1A2KDM4E
SCHEMBL11938179 0.64 CHRNB2 (0.44) ALDH1A1TSHRCYP1A2
SCHEMBL123189 0.64 CHRNB2 (0.44) ALDH1A1TSHRCYP1A2
SCHEMBL5855213 0.64 CHRNB2 (0.44) ALDH1A1TSHRCYP1A2
SCHEMBL10693930 0.64 LIPG (0.39) CYP3A4KCNH2
SCHEMBL2467827 0.64 ALDH1A1 (0.46) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266221-B1 Thermoplastic elastomer composition MITSUI PETROCHEMICAL IND (JP) 1994-03-09 EP disclosed