Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045358 | 0.91 | PIM1 (0.43) | P2RX4ALDH1A1ALOX15 | |
| SCHEMBL6045244 | 0.79 | PIM1 (0.41) | CA1CA2CA4CA9 | |
| SCHEMBL11817278 | 0.72 | CHRM2 (0.53) | — | |
| SCHEMBL6045312 | 0.72 | PIM1 (0.56) | ALDH1A1CACNA1B | |
| SCHEMBL6045308 | 0.72 | PIM1 (0.56) | ALDH1A1CACNA1B | |
| SCHEMBL23496876 | 0.69 | SIGMAR1 (0.54) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL6008090 | 0.69 | SIGMAR1 (0.54) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL3948948 | 0.69 | SIGMAR1 (0.54) | CA1CA2CA4CA9ALDH1A1 | |
| SCHEMBL9419617 | 0.69 | ALDH1A1 (0.64) | P2RX4ALDH1A1ALOX15CACNA1HCACNA1B | |
| SCHEMBL9419641 | 0.68 | ALDH1A1 (0.62) | P2RX4ALDH1A1ALOX15CACNA1HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371081-A | Useful in potentiating the cytotoxic effect of chemotherapeutic agents | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 1994-12-06 | — | — | US | claimed |
| WO-1993003729-A1 | N-SUBSTITUTED PHENOXAZINES FOR TREATING MULTIDRUG RESISTANT CANCER CELLS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | claimed |
| US-5371081-A | Useful in potentiating the cytotoxic effect of chemotherapeutic agents | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 1994-12-06 | — | — | US | disclosed |
| WO-1993003729-A1 | N-SUBSTITUTED PHENOXAZINES FOR TREATING MULTIDRUG RESISTANT CANCER CELLS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |