Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686471 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2MAPTCHRM2TSHRLMNA | |
| SCHEMBL5032298 | 0.81 | LMNA (0.43) | SMN1; SMN2MAPTTDP1CHRM2TSHR | |
| SCHEMBL5373491 | 0.79 | MCHR1 (0.40) | MAPTCHRM2LMNAKDM4EKMT2A | |
| SCHEMBL158540 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2MAPTTSHRKDM4EKMT2A | |
| SCHEMBL11526336 | 0.73 | NPC1 (0.42) | HTR2CHTR2BRAB9A | |
| SCHEMBL14211134 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTCHRM2TSHRLMNA | |
| SCHEMBL17506950 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTCHRM2TSHRLMNA | |
| SCHEMBL7787864 | 0.70 | FDPS (0.45) | SMN1; SMN2MAPTTDP1LMNAHTT | |
| SCHEMBL15337540 | 0.70 | MAPT (0.36) | SMN1; SMN2MAPTTDP1TSHRLMNA | |
| SCHEMBL15051368 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2MAPTTDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236674-B1 | Improved mineral filled rubber composites | DOW CORNING (US) | 1994-02-16 | — | — | EP | disclosed |
| EP-0236674-A2 | Improved mineral filled rubber composites | DOW CORNING CORPORATION (US) | 1987-09-16 | — | — | EP | disclosed |