Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928397 | 1.00 | KEAP1 (0.48) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL20513970 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL28841736 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL10914580 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL28135087 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL28135086 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL28135118 | 0.98 | KEAP1 (0.46) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| Hypophosphorous Acid SCHEMBL8145802 | 0.92 | KEAP1 (0.42) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL8145800 | 0.92 | KEAP1 (0.42) | KEAP1TDP1HDAC2HDAC8HDAC6 | |
| SCHEMBL3822270 | 0.86 | HDAC3 (0.52) | KEAP1TDP1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478624-B | Telomer of diethyl aluminum phosphinate and preparation method thereof | 兰州瑞朴科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| WO-2023138015-A1 | ALUMINUM DIETHYLPHOSPHINATE FLAME RETARDANT AND PREPARATION METHOD THEREFOR | 兰州瑞朴科技有限公司 | 2023-07-27 | — | — | WO | claimed |
| CN-114478624-A | Telomer of aluminum diethylphosphinate and preparation method thereof | 兰州瑞朴科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113929967-A | Phosphorus-nitrogen double salt and preparation method thereof, flame retardant and application thereof | 浙江新化化工股份有限公司 | 2022-01-14 | — | — | CN | claimed |
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | QUANTUM GENOMICS (FR) | 2021-12-07 | — | — | US | claimed |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Institut National de la Santé et de la Recherche Médicale (FR) | 2021-10-07 | — | — | US | claimed |
| CN-113462910-A | Method for enriching rare earth ions | 厦门钨业股份有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | claimed |
| CN-107637605-B | Flame retardant mixtures, their preparation and their use | 科莱恩塑料和涂料有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-111808133-A | Aluminum diethyl phosphinate material and preparation method thereof | 浙江新化化工股份有限公司 | 2020-10-23 | — | — | CN | claimed |
| US-10179797-B2 | Phosphinic peptide derivatives for use as MMP-12 inhibitors | DSM IP ASSETS B.V. (NL) | 2019-01-15 | — | — | US | claimed |
| EP-3380551-A1 | POLYMERIC FLAME RETARDANT MIXTURES | Clariant Plastics & Coatings Ltd (CH) | 2018-10-03 | — | — | EP | claimed |
| CN-108291050-A | POLYMERIC FLAME RETARDANT MIXTURES | 科莱恩塑料和涂料有限公司 | 2018-07-17 | — | — | CN | claimed |
| CN-107641136-A | Two organic group phosphinates, Its Preparation Method And Use | 科莱恩塑料和涂料有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-107641218-A | Flame retardant mixtures, their preparation and their use | 科莱恩塑料和涂料有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-107637605-A | Flame-retardant mixture, its preparation and application thereof | 科莱恩塑料和涂料有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-105017311-B | Rare earth phenylethyl phosphinate, and synthesis method and application thereof | 广东华南精细化工研究院有限公司 | 2017-04-19 | — | — | CN | claimed |
| US-5633111-A | Photoresist composition and article containing 1,2-quinonediazide and an organic phosphorous acid compound | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-27 | — | — | US | claimed |
| US-5254430-A | Lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-19 | — | — | US | claimed |
| US-5230988-A | Image exposure of plates of aluminum with phosphate or phosphonate compounds and basic compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1993-07-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | ANPEP, DNPEP, ENPEP | KEAP1 1303/4885TDP1 912/4885HDAC2 4172/4885 |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ANPEP, DNPEP, ENPEP | KEAP1 1303/4885TDP1 912/4885HDAC2 4172/4885 |
| US-10179797-B2 | Phosphinic peptide derivatives for use as MMP-12 inhibitors | MMP12, MMP13, MMP11 | KEAP1 3193/4885TDP1 1477/4885HDAC2 1356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.