Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | PRKCG | P05129 | 1/20 | 0.63 |
| ▸ | PRKACA | P17612 | 1/20 | 0.63 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.63 |
| ▸ | GSK3A | P49840 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | PRKX | P51817 | 1/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.63 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.63 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.63 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123739 | 0.93 | L3MBTL1 (0.71) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL29258273 | 0.88 | NAMPT (0.70) | — | |
| SCHEMBL1569157 | 0.88 | L3MBTL1 (0.77) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL30828595 | 0.86 | MMP13 (0.88) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL4503327 | 0.85 | MMP13 (0.69) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL7967175 | 0.84 | ALDH1A1 (0.55) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL95976 | 0.83 | MMP13 (0.68) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL28309717 | 0.83 | CA2 (0.68) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL171661 | 0.83 | SMN1; SMN2 (0.83) | MMP13CA2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL11628868 | 0.83 | CA2 (0.68) | MMP13CA2ROCK2RPS6KA5MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027949-A1 | NOVEL HYDROXYBIPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1994-12-08 | — | — | WO | disclosed |