SCHEMBL942286

SCHEMBL942286

C=C(C)c1ccc(Br)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP2A6 P11509 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ALOX15 P16050 1/20 0.41
NOS1 P29475 2/20 0.41
GSK3B P49841 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56361 0.85 MAPT (0.40) CES2CES1ALDH1A1MEN1MAPT
SCHEMBL22456719 0.83 LMNA (0.50) CES2CES1CA1CA2MAPT
SCHEMBL7596929 0.82 MAPT (0.38) CES2CES1ALDH1A1MEN1MAPT
SCHEMBL28660752 0.82 MAPT (0.38) CES2CES1ALDH1A1MEN1MAPT
SCHEMBL12449040 0.78 MAPT (0.32) CES2CES1ALDH1A1GSK3BMAPT
SCHEMBL28627481 0.77 ALDH1A1 (0.62) CES2CES1ALDH1A1GSK3BMEN1
SCHEMBL2643193 0.77 CYP2A6 (0.46) ALDH1A1CYP2A6MEN1MAPTKMT2A
SCHEMBL6343638 0.77 MAPT (0.55) CES2CES1ALDH1A1CYP2A6CA1
SCHEMBL21679933 0.77 CES2 (0.52) CES2CES1ALDH1A1CYP2A6CA1
SCHEMBL5546082 0.77 MAPT (0.35) CES2CES1ALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620791-B Method for preparing carbonyl compound by catalyzing oxidative cleavage of olefin compound through visible light excited aqueous solution quantum dots 大连理工大学 2022-10-14 CN claimed
CN-107077012-B Ophthalmic lens with reduced warpage 依视路国际公司 2021-07-27 CN claimed
US-20200140594-A1 CURABLE PETROLEUM RESIN, PREPARATION METHOD THEREOF, AND USE THEREOF KOLON INDUSTRIES, INC. (KR) 2020-05-07 US claimed
EP-3647333-A1 CURABLE PETROLEUM RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF Kolon Industries, Inc. (KR) 2020-05-06 EP claimed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US claimed
US-20170371075-A1 OPHTHALMIC LENS WITH REDUCED WARPAGE ESSILOR INTERNATIONAL (FR) 2017-12-28 US claimed
EP-3221726-A1 OPHTHALMIC LENS WITH REDUCED WARPAGE Essilor International (Compagnie Générale D'Optique) (FR) 2017-09-27 EP claimed
US-20150299841-A1 BASE FILM, LAMINATED STRUCTURE INCLUDING THE SAME, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2015-10-22 US claimed
US-9090721-B2 Highly heat resistant and highly strong acrylic copolymer, a resin composition comprising the same and an optical film and an IPS mode liquid crystal display device comprising the same LG CHEM, LTD. (KR) 2015-07-28 US claimed
US-8623960-B2 Resin composition for optical film, and polarizer protective film and liquid crystal display including the same LG CHEM, LTD. (KR) 2014-01-07 US claimed
US-20130190451-A1 RESIN COMPOSITION FOR OPTICAL FILM, AND POLARIZER PROTECTIVE FILM AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME LG CHEM, LTD. (KR) 2013-07-25 US claimed
CN-103214775-A Resin composition, polariscope protection film and liquid crystal display comprising polariscope protection film thereof used for optical film LG ELECTRONICS INC 2013-07-24 CN claimed
US-20130150546-A1 HIGHLY HEAT RESISTANT AND HIGHLY STRONG ACRYLIC COPOLYMER, A RESIN COMPOSITION COMPRISING THE SAME AND AN OPTICAL FILM AND AN IPS MODE LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME LG CHEM ,LTD. (KR) 2013-06-13 US claimed
CN-103080158-A Highly heat resistant and highly strong acrylic copolymer, a resin composition comprising the same and an optical film and an IPS mode liquid crystal display device comprising the same LG CHEMICAL LTD 2013-05-01 CN claimed
CN-102317333-A Acrylic resin composition, and optical film comprising same LG CHEMICAL LTD 2012-01-11 CN claimed
US-20110297896-A1 ACRYLIC RESIN COMPOSITION, AND OPTICAL FILM COMPRISING SAME LG CHEM, LTD. (KR) 2011-12-08 US claimed
US-4956123-A REACTING A STYRENE TYPE COMPOUND WITH A DIHALOACYL PEROXIDE TO MAKE A FLUOROALKYLAROMATIC ESTER NIPPON OILS & FATS COMPANY, LTD. (JP) 1990-09-11 US claimed
EP-0189275-B1 METHOD FOR MANUFACTURE OF FLUORINE-CONTAINING AROMATIC DERIVATIVES NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-10-18 EP claimed
US-4028486-A FIREPROOFING COPOLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-06-07 US claimed
US-3959398-A BROMINATION OF POLY(ALPHA-METHYL STYRENE), DEPOLYMERIZATION THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US claimed