Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356288 | 0.80 | L3MBTL1 (0.49) | KMT2AALDH1A1L3MBTL1MEN1TP53 | |
| Iodide SCHEMBL9424871 | 0.76 | KMT2A (0.40) | KMT2AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL30356302 | 0.74 | L3MBTL1 (0.53) | KMT2AALDH1A1L3MBTL1MEN1TP53 | |
| SCHEMBL7814232 | 0.74 | L3MBTL1 (0.53) | KMT2AALDH1A1L3MBTL1MEN1TP53 | |
| SCHEMBL11144881 | 0.74 | TSHR (0.45) | KMT2AALDH1A1LMNAMEN1TP53 | |
| SCHEMBL9424150 | 0.71 | KMT2A (0.38) | KMT2AALDH1A1LMNAMEN1TP53 | |
| SCHEMBL11166274 | 0.69 | L3MBTL1 (0.47) | KMT2AALDH1A1L3MBTL1MEN1TP53 | |
| SCHEMBL7593748 | 0.69 | L3MBTL1 (0.71) | KMT2AALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL16119538 | 0.68 | HTR7 (0.50) | ALDH1A1LMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9763218 | 0.67 | CA1 (0.44) | KMT2AALDH1A1MEN1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |