Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.56 |
| ▸ | AGT | P01019 | 2/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424366 | 1.00 | AGTR1 (0.56) | AGTR1AGTR2AGTGP6 | |
| SCHEMBL9567372 | 0.93 | AGT (0.56) | AGTR1AGTR2AGTGP6 | |
| SCHEMBL894 | 0.90 | GP6 (0.62) | AGTR1AGTR2AGTGP6 | |
| SCHEMBL498022 | 0.86 | AGTR2 (0.63) | AGTR1AGTR2AGT | |
| SCHEMBL9424121 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL9424118 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL9384588 | 0.85 | AGT (0.66) | AGTR1AGTR2AGT | |
| SCHEMBL9384590 | 0.85 | AGT (0.66) | AGTR1AGTR2AGT | |
| SCHEMBL9090 | 0.85 | AGTR2 (0.65) | AGTR1AGTR2AGTGP6 | |
| SCHEMBL610 | 0.85 | AGTR1 (0.62) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294633-A | Hypotensive, atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |