SCHEMBL9424978

SCHEMBL9424978

C=CC(=O)NC(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 3/20 0.51
RAD51 Q06609 1/20 0.47
ALDH1A1 P00352 5/20 0.45
MAPT P10636 2/20 0.45
RAB9A P51151 1/20 0.44
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SLC1A3 P43003 1/20 0.42
THRB P10828 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GFER P55789 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 2/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13134339 0.82 HSD17B10 (0.42) TGM2ALDH1A1MAPTKDM4ESMN1; SMN2
SCHEMBL2551644 0.82 ALDH1A1 (0.55) RAD51ALDH1A1MAPTRAB9ANFKB1
SCHEMBL13134341 0.80 KMT2A (0.44) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL5279705 0.78 ALDH1A1 (0.52) RAD51ALDH1A1MAPTRAB9ANFKB1
SCHEMBL3074679 0.78 ALDH1A1 (0.52) RAD51ALDH1A1MAPTRAB9ANFKB1
SCHEMBL7513100 0.77 RAD51 (0.50) TGM2RAD51ALDH1A1MAPTRAB9A
SCHEMBL13134325 0.76 TGM2 (0.35) TGM2ALDH1A1MAPTMEN1KMT2A
SCHEMBL13134326 0.76 TGM2 (0.35) TGM2LMNA
SCHEMBL13134327 0.76 MMP2 (0.39) TGM2LMNA
SCHEMBL13134354 0.76 PTPN1 (0.43) TGM2ALDH1A1MAPTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US disclosed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP disclosed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US disclosed
EP-0177122-A2 Acrylamide derivatives Nippon Paint Co., Ltd. (JP) 1986-04-09 EP disclosed