Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806983 | 0.89 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14876546 | 0.88 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9425197 | 0.77 | HSD17B10 (0.36) | KDM4EMAPTHPGDGAALMNA | |
| SCHEMBL5276997 | 0.77 | CA2 (0.45) | ALDH1A1KDM4EKMT2ANPC1 | |
| SCHEMBL2799283 | 0.77 | MAPT (0.66) | L3MBTL1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL520569 | 0.76 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL12226493 | 0.76 | L3MBTL1 (0.72) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2812377 | 0.76 | ABHD6 (0.55) | ALDH1A1KDM4EMAPTALOX15NPSR1 | |
| SCHEMBL10383656 | 0.75 | ABCB1 (0.56) | L3MBTL1ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL14876328 | 0.74 | L3MBTL1 (0.66) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318963-A | Heterocyclic hydrazide derivatives of monocyclic β-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | disclosed |