Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426187 | 0.78 | PRSS1 (0.46) | NOS3NOS1NOS2PRSS1PRSS2 | |
| SCHEMBL9426333 | 0.78 | LMNA (0.48) | GAAALDH1A1KDM4ELMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9426233 | 0.77 | PRSS1 (0.45) | NOS3NOS1NOS2PRSS1PRSS2 | |
| SCHEMBL28724676 | 0.68 | PLAU (0.48) | BAZ2BNOS3NOS1NOS2MAPT | |
| Thiourea SCHEMBL28925187 | 0.67 | ALDH1A1 (0.53) | PRSS1PRSS2C1SPRSS3GAA | |
| SCHEMBL9425438 | 0.67 | CCR1 (0.31) | NOS3NOS1NOS2PRSS1PRSS2 | |
| SCHEMBL9425718 | 0.67 | NOS3 (0.32) | BAZ2BNOS3NOS2PRSS1PRSS2 | |
| SCHEMBL24121412 | 0.65 | PRSS1 (0.52) | NOS3NOS1NOS2PRSS1PRSS2 | |
| SCHEMBL7718641 | 0.65 | LMNA (0.54) | LMNA | |
| SCHEMBL18210628 | 0.64 | PDE2A (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354761-A | Antiprotozoa agents | CIBA-GEIGY CORP. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0495749-A1 | Bipyridines | CIBA-GEIGY AG (CH) | 1992-07-22 | — | — | EP | disclosed |