Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425761 | 0.88 | MEN1 (0.44) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9159359 | 0.86 | MEN1 (0.46) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL24942562 | 0.77 | MEN1 (0.47) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL19312859 | 0.70 | CA12 (0.43) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL4373921 | 0.66 | MEN1 (0.47) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL20261069 | 0.66 | MEN1 (0.52) | MEN1MAPK1KMT2A | |
| SCHEMBL15743640 | 0.66 | S1PR2 (0.39) | — | |
| SCHEMBL19196529 | 0.65 | FAAH (0.64) | MEN1FAAHMAPK1KMT2A | |
| SCHEMBL9151135 | 0.65 | EPHX1 (0.44) | MEN1FAAHKMT2A | |
| SCHEMBL30890868 | 0.65 | DNM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358946-A | Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-25 | — | — | US | disclosed |