SCHEMBL9425486

SCHEMBL9425486

CC(C=O)CCCCCC(=O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9425568 0.94 CTSK (0.30)
SCHEMBL10585580 0.78 ALDH1A1 (0.42) LMNAALDH1A1MAPT
SCHEMBL6545080 0.77 TSHR (0.42) LMNAALDH1A1
SCHEMBL9626170 0.76 ALDH1A1 (0.40) LMNAALDH1A1MAPT
SCHEMBL31285293 0.76 DGKA (0.50) LMNAALDH1A1MAPT
SCHEMBL8458653 0.76 LMNA (0.50) LMNAALDH1A1
SCHEMBL4936173 0.76 DGKA (0.50) LMNAALDH1A1MAPT
SCHEMBL1595383 0.76 TSHR (0.44) LMNAALDH1A1
SCHEMBL25606204 0.76 LMNA (0.50) LMNAALDH1A1
SCHEMBL4810374 0.76 LMNA (0.50) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5348890-A In an aqueous solvent NOF CORPORATION (JP) 1994-09-20 US disclosed
EP-0545367-A1 Trioxane derivatives, process for the preparation thereof, and method for the chemiluminescence NOF CORPORATION (JP) 1993-06-09 EP disclosed