Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585580 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRDGKACYP3A4 | |
| SCHEMBL6545080 | 0.83 | TSHR (0.42) | ALDH1A1LMNATSHRRECQLDGKA | |
| SCHEMBL6545278 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL7046887 | 0.79 | DGKA (0.50) | ALDH1A1LMNATSHRDGKAALOX15 | |
| SCHEMBL31285293 | 0.79 | DGKA (0.50) | ALDH1A1LMNATSHRDGKAALOX15 | |
| SCHEMBL4863534 | 0.79 | TSHR (0.31) | ALDH1A1LMNATSHR | |
| SCHEMBL1595383 | 0.79 | TSHR (0.44) | ALDH1A1LMNATSHRALOX15HSD17B10 | |
| SCHEMBL4936173 | 0.79 | DGKA (0.50) | ALDH1A1LMNATSHRDGKAALOX15 | |
| SCHEMBL8864847 | 0.77 | DUT (0.36) | ALDH1A1LMNATSHRDGKA | |
| SCHEMBL9425486 | 0.76 | LMNA (0.33) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169033-B1 | INHIBITORS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS | SCHERING CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0169033-A2 | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |