Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051 | 0.80 | PSIP1 (0.47) | ALDH1A1LMNAL3MBTL1HDAC3HDAC4 | |
| SCHEMBL9043466 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL5664985 | 0.78 | HTR6 (0.47) | ALDH1A1HTTL3MBTL1MAPT | |
| SCHEMBL8791000 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL4629972 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL8415191 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL16591739 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL29516114 | 0.74 | LMNA (0.61) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL383077 | 0.74 | LMNA (0.61) | ALDH1A1HTTKDM4EHPGDGAA | |
| SCHEMBL7208046 | 0.73 | KDM4E (0.65) | ALDH1A1HTTKDM4EHDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276159-A | Antitumor | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-04 | — | — | US | disclosed |