Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426865 | 0.87 | FAAH (0.58) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9154459 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9159580 | 0.83 | MEN1 (0.48) | NPC1MEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL9426435 | 0.82 | MEN1 (0.47) | NPC1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9426828 | 0.80 | MTNR1B (0.64) | NPC1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9425645 | 0.76 | NPC1 (0.54) | NPC1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9155811 | 0.75 | NPC1 (0.53) | NPC1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9426204 | 0.74 | KMT2A (0.47) | NPC1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9154232 | 0.73 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL12541529 | 0.72 | NPC1 (0.82) | NPC1MEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | claimed |
| US-5340809-A | Antihypoxic, antiischemic agents | ADIR ET COMPAGNIE (FR) | 1994-08-23 | — | — | US | disclosed |